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Problems of prescribing immunosupressive therapy to a rheumatological patient with chronic viral infection. Clinical case presentation

https://doi.org/10.24884/1609-2201-2024-103-2-77-81

Abstract

In rheumatological practice, overlap syndrome (“overlap-syndrome”) is often encountered, which is manifested by the presence of diagnostic signs of more than one of the six classic systemic autoimmune diseases. The presence of chronic viral infections significantly complicates drug therapy. The article presents the history of the disease of a 46-year-old patient who was diagnosed with an overlap syndrome in the form of a combination of idiopathic polymyositis with antisynthetase syndrome and rheumatoid arthritis. The complexity of treating the patient was determined by the identification of active chronic viral hepatitis C. A multidisciplinary approach to the management of the patient in compliance with the principles of rational pharmacotherapy is described.

About the Authors

M. D. Tishkina
Clinical Rheumatology Hospital 25

Maria D. Tishkina, rheumatologist

St. Petersburg, Bolshaya Podyacheskaya st., 30, 190068



D. A. Davydov
Pavlov University
Russian Federation

Denis A. Davydov, rheumatologist of cardiology department No. 2, Clinic of the Research Institute of Rheumatology and Allergology

Saint Petersburg



E. A. Bruchkus
Pavlov University
Russian Federation

Elena A. Bruchkus, rheumatologist, Head of Cardiology Department No. 2, Clinic of the Research Institute of Rheumatology and Allergology

Saint Petersburg



I. I. Nesterovich
Pavlov University
Russian Federation

Irina I. Nesterovich, Dr. of Sci. (Med.), Professor of the Department of Hospital Therapy with a Course of Allergology and Immunology named after ac. M. V. Chernorutsky with clinic

Saint Petersburg



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Review

For citations:


Tishkina M.D., Davydov D.A., Bruchkus E.A., Nesterovich I.I. Problems of prescribing immunosupressive therapy to a rheumatological patient with chronic viral infection. Clinical case presentation. New St. Petersburg Medical Records. 2024;(2):77-81. (In Russ.) https://doi.org/10.24884/1609-2201-2024-103-2-77-81

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ISSN 1609-2201 (Print)