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Circadian rhythms in some nephrological diseases

https://doi.org/10.24884/1609-2201-2025-104-1-54-58

Abstract

By now, it is well known that the circadian clock is an evolutionarily preserved mechanism that adapts the physiological processes of the body to circadian cycles. Circadian rhythms of kidney function are an integral part of kidney physiology.
The most well-known general data on the mechanism of the circadian clock, as well as the features of the course of some nephrological diseases in terms of circadian rhythms, are briefly considered.
It has to be stated that there are very few studies on the effect of circadian rhythms on the course of kidney disease, especially clinical studies.

About the Authors

V. N. Mineev
Pavlov University
Russian Federation

Valeriy N. Mineev, Professor of the M. V. Chernorutskiy Department of Hospital Internal Medicine with Course in Allergology and Immunology

6–8, L’va Tolstogo str., Saint Petersburg, 197022



D. I. Mamedova
Pavlov University
Russian Federation

Jamilya I. Mamedova, 6th year student of the Faculty of Medicine

6–8, L’va Tolstogo str., Saint Petersburg, 197022



References

1. Agriesti F., Cela O., Capitanio N. “Time Is out of Joint” in Pluripotent Stem Cells: How and Why. Int. J. Mol. Sci. 2024;25:2063. https://doi. org/10.3390/ijms25042063.

2. Dictionary of winged words and expressions. Moscow, Lokid-Press, 2003. URL: https://dic.academic.ru/dic.nsf/dic_wingwords/2349/%D0%A0%D0%B0%D1%81%D0%BF%D0%B0%D0%BB%D0%B0%D1%81%D1%8C?ysclid=m6nnf9kw1218482757 (accessed: 20.02.25). (In Russ.).

3. Dierickx P., Van Laake L. W., Geijsen N. Circadian clocks: from stem cells to tissue homeostasis and regeneration. EMBO Rep. 2018;19(1):18–28. https://doi.org/10.15252/embr.201745130.

4. Costello H. M., Johnston J. G., Juffre A. et al. Circadian clocks of the kidney: function, mechanism, and regulation. Physiol Rev. 2022;102(4):1669–1701. https://doi.org/10.1152/physrev.00045.2021.

5. Preston R., Chrisp R., Dudek M. et al. The glomerular circadian clock temporally regulates basement membrane dynamics and the podocyte glucocorticoid response. Kidney Int. 2025;107(1):99–115. https://doi.org/10.1016/j.kint.2024.10.016.

6. Mineev V. N. Zimnitskiy’s test – “circadian nephromonitoring”. University Therapeutic Journal. 2024;6(2):46–50. (In Russ.). https:// doi.org/ https://doi.org/10.56871/UTJ.2024.29.99.005.

7. Bryukhanov V. M., Zvereva A. J. The kidney role in regulation of circade rithms of the organism. Nephrology (Saint-Petersburg). 2010;14(3):17–31. (In Russ.). https://doi.org/10.24884/1561-6274-2010-14-3-17-31.

8. Stow L. R, Gumz M. L. The circadian clock in the kidney. J Am Soc Nephrol. 2011;22(4):598–604. https://doi.org/ 10.1681/ASN.2010080803.

9. Firsov D., Bonny O. Circadian rhythms and the kidney. Nat Rev Nephrol. 2018;14(10):626–635. https://doi.org/ 10.1038/s41581-018-0048-9.

10. Solocinski K., Gumz M. L. The Circadian Clock in the Regulation of Renal Rhythms. J Biol Rhythms. 2015;30(6):470–486. https://doi.org/10.1177/0748730415610879.

11. Fedoseev G. B., Aghajanyan N. A., Voronov I. B. et al. Chronobiology of the lungs / eds by G. B. Fedoseev, I. B. Voronov. Leningrad, Nauka, Leningrad department, 1987. 102 p. (In Russ.).

12. Shishkina I. V., Movchan E. A., Tov N. L. et al. Circadian rhythm of arterial pressure in different clinical variants of chronic glomerulonephritis. Nephrology (Saint-Petersburg). 2001;5(3):160–161. (In Russ.).

13. Mosina N. V., Essaian A. M., Rumyantsev A. Sh. Circadian rhythms of arterial pressure in patients with chronic glomerulonephritis and diabetic nephropathy in the stage of chronic renal failure. Nephrology (Saint-Petersburg). 2004;8(3):62–66. (In Russ.) https://doi.org/10.24884/1561-6274-2004-8-3-62-66.

14. Fukuda M., Goto N., Kimura G. Hypothesis on renal mechanism of non-dipper pattern of circadian blood pressure rhythm. Med Hypotheses. 2006;67(4):802–806. https://doi.org/10.1016/j.mehy.2006.04.024.

15. Agarwal R. Regulation of circadian blood pressure: from mice to astronauts. Curr Opin Nephrol Hypertens. 2010;19(1):51–58. https://doi.org/10.1097/MNH.0b013e3283336ddb.

16. Buijsen J. G., van Acker B. A., Koomen G. C. et al. Circadian rhythm of glomerular filtration rate in patients after kidney transplantation. Nephrol Dial Transplant. 1994;9(9):1330–1333.

17. Gatzka C. D., Schobel H. P., Klingbeil A. U. et al. Normalization of circadian blood pressure profiles after renal transplantation. Transplantation. 1995;59(9):1270–1274.

18. Hill A. M., Crislip G. R., Stowie A. et al. Environmental circadian disruption suppresses rhythms in kidney function and accelerates excretion of renal injury markers in urine of male hypertensive rats. Am J Physiol Renal Physiol. 2021;320:F224–F233. https://doi.org/10.1152/ajprenal.00421. 2020.

19. Jin M., Teng F., Cao B. et al. Integrative analysis of the association between circadian rhythm and lupus nephritis. Clin Kidney J. 2023;16(9):1489–1499. https://doi.org/10.1093/ckj/sfad092.

20. Chen K., Wang Y., Li D. et al. Biological clock regulation by the PER gene family: a new perspective on tumor development. Front Cell Dev Biol. 2024;12:1332506. https://doi.org/10.3389/fcell.2024.1332506.

21. Mazzoccoli G., Piepoli A., Carella M. et al. Altered expression of the clock gene machinery in kidney cancer patients. Biomed Pharmacother. 2012;66(3):175–9. https://doi.org/10.1016/j.biopha. 2011.11.007.

22. De Lavallaz L., Musso C.G. Chronobiology in nephrology: the influence of circadian rhythms on renal handling of drugs and renal disease treatment. Int Urol Nephrol. 2018;50(12):2221–2228. https://doi.org/10.1007/s11255-018-2001-z.

23. Preston R., Chrisp R., Dudek M. et al. The glomerular circadian clock temporally regulates basement membrane dynamics and the podocyte glucocorticoid response. Kidney Int. 2025;107(1):99–115. https://doi.org/ 10.1016/j.kint.2024.10.016.

24. Titova V. A. The role of podocytes in the development of glomerular sclerosis. Nephrology (Saint-Petersburg). 1999;3(2):7–18. (In Russ.). https://doi.org/10.24884/1561-6274-1999-3-2-7-18.


Review

For citations:


Mineev V.N., Mamedova D.I. Circadian rhythms in some nephrological diseases. New St. Petersburg Medical Records. 2025;(1):54-58. (In Russ.) https://doi.org/10.24884/1609-2201-2025-104-1-54-58

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ISSN 1609-2201 (Print)